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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c4a0d2c647d7b87d523f94239e5b3ceb103532582cde0d85540604d57a3fd12' 
  AND token = 'OhHj4Cb/LVIQV9JwM6lJS6cZJDeITBb6Sg4dF3NjaTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}