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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3095f3a18a1d43429f500ba35c6461f391e007e5ac461eb7db540ee864c53b73' 
  AND token = '8Tt65PBf5bTUKsN8ej+VmOqJfNCdZWKnfsY8sox/Pnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}