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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bda960c0acf1a3649186bc61ddcb4ab7eef4d707f5341c1a87c40d32f51c366' 
  AND token = 'HMPbnLA9/yP0meMAgBp73LKCKRU1KZBlCs0Vc/00oz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}