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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972d459db6eb8eebb3512a72f8e9012bc46921c50a5c1022706945c1e56021d2' 
  AND token = '1WdQmVI1tE4uc22HSv9dW3RPxRZ6yIfLNRLJpQpgHTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}