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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ad7b7a010a584e2f1f6dc59430629750ff19f42afa0069f68a7715d49b7e284' 
  AND token = 'A1KHAXTjZ9wi/tk1+raPI4+xquvs80Xkq3vz9PSCT4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}