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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35c4c914bbb679f2d51e55d758314d7d9e7b6986b9333514257fc0b1b3919c02' 
  AND token = '5vN+QiB95El4YbXWM41aak/nwNCawwY4pHTiUSzouag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}