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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c23c9e7eb5ffb3f7b73d5c94409f0f8efb265d0b0309849141a881b2839bbe' 
  AND token = 'jeqki5myYg+BxPa8dOtT3dA1TikPw42UERDqES4F8PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}