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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41e8203fad44505334d70ba6d0e11753d83c690880ae7bd60d1b8c4b48532301' 
  AND token = 'fmdYE5kNUzt21Wy/0OYdr4bmcp3/oNTKOnXOB9Li830=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}