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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177b4426b4d996facf76c147202def4e2c9514936663b9115ac10f9582c9757c' 
  AND token = '1htza/6FHpeIkE6W28hUmPZzKfKYLDPU7jIouA30olI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}