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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5038aa76b0c8387e57b56b49ffcd8660f3c339a2102e574ca91f6ef55c6ba310' 
  AND token = 'M5i+Xctb7Qc5BM0tn4PoiXQXc9A1mEsuWF5P+ygNEhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}