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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c914ef378f6a26e4cccc1fafb81a9503be4ab8f8528d3291e65407baad721242' 
  AND token = 'MqWPP3w9nSmuCIk4XLGcU/oho10dnm5SO6hr/+Pq+1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}