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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c88e5586ae00e66dbf070a887b8a81b4187be417da840424f0fbb1dfbd1de4b' 
  AND token = 'LghpDCgqXD48F2TCweeUrM3wzBgAZx90ExmbZYE9CGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}