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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e208852930384a38d3ba3b109b7bef654d6d9c9047086ec2e110ed6e7e49cb8' 
  AND token = '3PyplRf+cxMogfOEMFnX4F1AZdtcZ/FewMw4/TuaZIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}