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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a45ebefd93643d8f956cf599f71d7d4d47d3a1fc8741f18b32916440cbe4a3' 
  AND token = 'IrdPyiUB2jM4jbnCKGSSERfeAiZiq75XVtpYfuQBkYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}