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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2758fb3c053318e3d2aa8dc34b6bb2169fa5f07c73e583f64f31785badfa29' 
  AND token = 'NAIo0wQjuwYwMrtTQwvrTckkJbatbEaIuXGUkVKOtfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}