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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2b60ac43a037f94a8dc510e504d23e76468d10d81bd80fa002cd66330e04155' 
  AND token = 'sxyI3kJ3Q63neWCWMlxlmTIH6SXKyiSa2qqREyZfvSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}