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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d00b3603a47a3dec40965e73394fc1ade0171a2887d4bb1e00d342e715a88a7' 
  AND token = '50RNkeeLOZtGkGSoyRrA5eDHyy/0MRcQd1nPWLvCcP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}