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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d8b72cac45d756425f87c936c5b0cd7cb9250cb7dcc51a0352ae1f765c905d' 
  AND token = 'W6Sksw/1sFl8+a9ksOl4QBIEu94L/3p1nPZt9/xuxCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}