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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd99d48d63d7a956fd9ed7ad1f21a6796260f8cd4c49fd96752ba6cc2f1bee0' 
  AND token = '/lc1D4df+vFS5CBvKF+ADIgG47zrMU+9P3+tp3GCoWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}