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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ca028c4b485454ec67a3cc5206586a1e0d387a601af966b29d663d6c791564' 
  AND token = '+RF1q9mlooycBP42qXfIvHqdfshDChApu5ila6YN/Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}