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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e3d3b4dab222e99ab6435988447cfd597f6932caf508b29146431328d422f7' 
  AND token = 'Fy2w1jbq2GY5xSJT20Xz2IU396IXW35wIY0NC/WI3/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}