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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9bc0d75329255d70399e92f404b9554165d9aa1e9c64a2ed712c71c9cb76201' 
  AND token = 'cmlaUKrdWSB0D1rVYVZu3J9GqzyhHwMEO8vYQfe3NIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}