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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e68b37a4d40ce9578b200e1d2bca92a4ed5656724aa1a4ec0ef0d503e64280' 
  AND token = 'X0/DUB1VgFI/lr9NhSFSsiC6lcvoMyRQ+NF19mmq0uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}