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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a232ab6553378eff6e3f6cf4b3cd70ba5161f2a65f04ff2da0af2cc3a18a163' 
  AND token = '26ed9R5Otd91Eg8QmR6Xn9Hc6a910Z0MEoyPdbQUEP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}