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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6add333f1315404c83fa67247b9b2f3905c3255603e73d676ae73c9701cc121' 
  AND token = 'fqa2YTqQevFLeYMKO9Qcbpd37g+Cfk5p0PBYTUx+TZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}