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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fe6f85b96eb1049e160325edb6edb3ca55eda1ba8081aeac7fbb7c30bccbc8f' 
  AND token = 'z0Zj0KvGTe96D58AkzQo+G11OW9WGNqVWp7inknCjLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}