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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b41ef643f1e89271df994c6ac3a6695995b8ce5f0b02280f56413a1c5e9a118' 
  AND token = 'ntScgSmxuA+mNPDw/5ScaX8kYR2hmHLYdcvROa7SbbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}