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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b883e04f0478161f7fbe5301f5ea3359600e45cd4f4e3a21180b39fea412b26f' 
  AND token = 'BTR5O9QYoUF94Vi+W1layJSgowr9wobpLAqOyUtTBlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}