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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9f20b8c1ecd1e1654d9c7741c1a5106e01c511c0420b004ffdb8e933309a30' 
  AND token = 'IGsw+yb8K+NKGfAfo3aTMEXcuC7fO8QeZl5e6S+ST5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}