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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5f2bbfb32f3e8792f278ce51abcf2ae88abbf85a59ca30bf8c3871ede61110b' 
  AND token = 'MEIsL3cdbFRPP1rqLKdozG3NbfgeUxy0QfwxrpvmQkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}