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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e216316f5c9f714be727b24f9f8e1205a5425bf9bfa91cf450a48ee57429d2' 
  AND token = 'S664iktIRCQgsVYUHMX4Jk0nLyyRj0twvOgIIAF6RX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}