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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f33b8bb8037b1a72a0badee409cc15f7f385e2c8ec30c01b114dcbbf6dc90a03' 
  AND token = 'ioZ34/NZ6fHqwO+8SR6zOvjSiSaXFowttvmYjqwLdpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}