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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e9778182d55b81274b8fbaa5ec2d754568a7fc0cf453b4fce66a81b07f2626' 
  AND token = 'NJG47MeSblUZqDEUjUap8jfjoVTW/jlPF2BabuLD1lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}