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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb57181b121d097c47e7e53b904c786afe4080a1bfced7f6727774aa486c4430' 
  AND token = 'u4zV9nTW4IvZ/H5ZRKiHL4tltYstnnuOHHM6jhUAqWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}