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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22594173bf9d6fddae478389326a179bd9eb2c999918ef05ac508069b8789da' 
  AND token = 'VGkKbeXhPky4dXW1ERUdoXMbMTH4HzQSIqD8g1O/WWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}