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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396ed9bfd514602239b93ff1dde1928d7173faa18f96c86738f177ff01389caa' 
  AND token = 'rNpHZ0Th1RSY+K+T7/XLZu/0b5basa3Q9LjMU0DLkw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}