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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c86c4c34bfc20c912a0f06a784daf20e65e38d3d06d863b0e621ecabd3e037c' 
  AND token = 'A6HWUbpRi1MKjB/L1tJDM97M01aWWJlXv4YWNxx2ayQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}