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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc964441f9f508aee7c68659241b2e2d72b122b5c8fd7b42691efbe30370ffd' 
  AND token = 'vUAtMR0iNk9IAnMaWSJZtRg1CnYvd1WIMi1GIt4kzcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}