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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c7fc3b11412f7ceeb4a493908df9f581084a32274c0127f1600e280b07604a4' 
  AND token = 'vY9CgKAFbKagFUDbkyhQBKycerSIto0+61+aOCEEyGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}