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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd68ea20aa3f131d61708f9709c1014bcd9cb1f720947ed12b98390010d80cf5a' 
  AND token = 'lhlWTnXFe/MV1unZ+69NwapWxGpuuY7sEGq59Bm2fqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}