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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b467f9b05b982df76d74c4b0c660accc46cb5a0f29f9932e3205ea0a4996353' 
  AND token = 'wNGz61zpN2ayoepXIgQl9hl4xxCh18/9LiDEpe4r7Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}