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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c772d945a99a21835b7344bd562daaf3f69f44de7a562e43cf1a6d3f9883970b' 
  AND token = '27egrzFH7PqGBFskojAf/FAGP/RjEajNVAHFFAhtiRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}