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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28980e049f3da74d10641a270089531405fa3b0ddc119dca863fadd9739465ba' 
  AND token = 'vlzcsMRxK9FlWmPYHuNF7PmFH0ZLGyuqFo5UKC9NuLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}