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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99589341dfb07780b0dc8dcd6677e21409a558a7cfe8c56747676cffee04e2c9' 
  AND token = 'wOKE51AHHWHPIu7G55a/876s4Z+vFq6Ybb9DM6VT+Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}