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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6195ff86ab40b4524c4a76b2114e3ba02bcffa6e712f64164e9fb0a0809ad120' 
  AND token = 'DqW1P9qZFWmYPiVMfw0bMk/Iy4rcVUhX7Wa9ZefU880=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}