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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647fdaed84a0406de67e0c8bdfd863279d20b4b49d1e7b4da7e6a4901ab2e225' 
  AND token = 'SKEwIF5SANihVcczLpd/5J8+iIqtvQ5ZnKykVMSZj/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}