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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a4b2c4d7df15ed53b4c6774500488b43493f4508a54815313a3e822e5f8656' 
  AND token = 'VtutphfyW8avNxLzFCtIxUhHlqLbwp1eKDEtH76Ffbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}