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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c01912b22b02b314392b0a68763ef1a6c0a8364c4e25d1fd358409ab8ecbd27' 
  AND token = 'pGZMJ50sv+6/uORaupSBRRDtESkss2GqeBye5m5JTiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}