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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f249a8aface6cab8487b073936aaedf97c7a5bf1fa62742c12d1a3f455ea234c' 
  AND token = 'SZWowMDxDcI4BkHFPiudsRXRVS2adMyh3EXGvLwf+vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}