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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5cc32a397b4581c4cc5ca84b35cd249e5aec4be85e1a700850110024cb76f85' 
  AND token = 'uE+zRwJBLz3yI6rLsAkn+s8x53f3Bf7gb/wRofu0oxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}